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阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T8172	2-O-α-D-Glucopyranosyl-L-ascorbic Acid	ASCORBYL GLUCOSIDE	Others
	2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE), a glucoside derivative of ascorbic acid, demonstrates anti-cancer activity following enzymatic hydrolysis to ascorbic acid.		Others
T19389	L-Ascorbic acid 2-phosphate magnesium	2-Phospho-L-ascorbic acid magnesium	Phosphatase , Phosphorylase
	L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.It is a long-acting vitamin C derivative that can stimulate...		Phosphatase , Phosphorylase
T0752	Ascorbyl palmitate	L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate	Reactive Oxygen Species , Endogenous Metabolite
	Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C.		Reactive Oxygen Species , Endogenous Metabolite
T19390	L-Ascorbic acid 2-phosphate	2-Phospho-L-ascorbic acid	Others
	L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and...		Others
T23757	Ascorbic acid, rutoside drug combination	Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin
	Ascorbic acid, rutoside drug combination is used for treating diabetic retinopathy.
T30154	Ascorbyl myristate	Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid
	Ascorbyl myristate is a bioactive chemical.
T16562	Ponceau 4R	Acid Red 18,New Coccine	Others
	Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usual...		Others
T4313	Tinoridine hydrochloride	Nonflamin,Y-3642 hydrochloride	COX , Glutathione Peroxidase
	Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid...		COX , Glutathione Peroxidase
T24970	1'-Ethylascorbigen
	1'-Ethylascorbigen releases ascorbic acid in acidic solution results in an increase in the cells' ability to produce PGE2 & LTB4. It has been shown to inhibit the growth of experimental murine tumors.
T36459	CAY10730
	CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia. In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excit...
T76101	Ascorbate oxidase
	Ascorbate oxidase, or Vitamin C oxidase, is a redox (REDOX) enzyme that plays a crucial role in extracellular matrix regulation by catalyzing the oxidation of ascorbic acid to dehydroascorbic acid in the presence of oxyg...

Compounds

2-O-α-D-Glucopyranosyl-L-ascorbic Acid

T8172

Synonym: ASCORBYL GLUCOSIDE

Target: Others

L-Ascorbic acid 2-phosphate magnesium

T19389

Synonym: 2-Phospho-L-ascorbic acid magnesium

Target: Phosphatase, Phosphorylase

Ascorbyl palmitate

T0752

Synonym: L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate

Target: Reactive Oxygen Species, Endogenous Metabolite

L-Ascorbic acid 2-phosphate

T19390

Synonym: 2-Phospho-L-ascorbic acid

Target: Others

Ascorbic acid, rutoside drug combination

T23757

Synonym: Rutinoscorbin,Rutascorbin,Ruta C 60,Cerutin

Target:

Ascorbyl myristate

T30154

Synonym: Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid

Target:

Ponceau 4R

T16562

Synonym: Acid Red 18,New Coccine

Target: Others

Tinoridine hydrochloride

T4313

Synonym: Nonflamin,Y-3642 hydrochloride

Target: COX, Glutathione Peroxidase

カタログ番号	製品名	別名	ターゲット
T0928	L-Ascorbic acid	Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate	Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-...
T7966	3-O-Ethyl-L-ascorbic acid		Tyrosinase
	3-O-Ethyl-L-ascorbic acid is a cosmetic tyrosinase inhibitor with whitening ability and is a stabilized vitamin C derivative. It also has antioxidant properties.		Tyrosinase
T6674	L-Ascorbic acid sodium salt	(+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,Sodium L-ascorbate	Apoptosis , Others , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
T2185	L-Ascorbic acid 2-phosphate trisodium	L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate	Reactive Oxygen Species , c-Met/HGFR , Endogenous Metabolite
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
T83876	L-Ascorbic Acid 6-stearate	L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid
	L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (...
T10077	2-O-β-D-Glucopyranosyl-L-ascorbic acid	AA-2βG	Others
	2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) is isolated from Lycium Fruit. It is a stable vitamin C analog with anti-tumor activity.		Others
T4917	Dehydroascorbic acid	(L)-Dehydroascorbic acid	Endogenous Metabolite
	L-Dehydro Ascorbic Acid is the reversibly oxidized form of ascorbic acid;Dehydroascorbic acid ((L)-Dehydroascorbic acid), a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experi...		Endogenous Metabolite
T8949	UDP-g acid		Others
	UDP-g acid is a sugar used in the production of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid		Others
T5064	Oxalic acid dihydrate	Ethanedioic acid dihydrate	Others , Endogenous Metabolite
	Oxalic acid dihydrate (Ethanedioic acid dihydrate) is a strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized...		Others , Endogenous Metabolite
T2O2680	Oxalic acid	Wood bleach,Aktisal,Aquisal,Ethanedioic acid	Others , Endogenous Metabolite
	Oxalic acid is a strong dicarboxylic acid occurring in many plants. Oxalic acid is produced in the body by metabolism of glyoxylic acid or ascorbic acid.		Others , Endogenous Metabolite
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T4719	1,4-D-Gulonolactone	D-Gulonic acid γ-lactone	Others , Endogenous Metabolite
	1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (also known as reduced ascorbic acid, RAA) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8), which catalyzes the last step of the biosynthesis...		Others , Endogenous Metabolite
T5216	Calcium L-Threonate	L-Threonic acid Calcium Salt	Others , Endogenous Metabolite
	Calcium L-Threonate (L-Threonic acid Calcium Saltr) is probably derived from glycated proteins or from the degradation of ascorbic acid. Calcium L-Threonate is a normal component is aqeous humour and blood. Calcium L-Thr...		Others , Endogenous Metabolite
T5796	Plantainoside D	Isoplantamajoside	RAAS , PKC
	Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ...		RAAS , PKC